More and more commuters and business travelers are using their time on the long-distance train for mobile working. This potentially places different demands on work than working in a stationary office. The aim of the project is to investigate how well different work tasks can be carried out on long-distance trains compared to a stationary office. Particular attention will be paid to the physical and mental stress caused by mobile working. Based on this, work design measures will be derived to support both employers and employees in working under safe and healthy conditions.